A Novel Automatic Method of Cortical and Cancellous Bone Segmentation Based on Marrow Compartment
Visual inspection has confirmed successful segmentation of all data sets using the new method for two years in our lab. The segmentation results from the new method were also compared with those from a manual method and those from a published method, the so-called Helterbrand method. The mean values of the cancellous bone volume measured by the new method were not significantly different from those measured by the manual method, while there were significant differences between the mean values measured by the Helterbrand method and the manual method. The coefficient of variation was approximately 1% for the new method, demonstrating good precision. The variance of the new method was statistically significantly smaller than that of the manual method, which confirmed the better repeatability of the new method compared with the manual technique.
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